Tujunga Medical Group News

Considerations about Detecting Airflow Obstruction in Smoking Cessation Trials

Smoking-related diseasesSmoking has been labeled the most important preventable cause of death and disease. The lack of specific treatment for smoking-related diseases and the recognition of the benefits of smoking cessation justify the dedication of significant scientific and community resources to increase rates of smoking cessation. Among smoking-related diseases, COPD is currently a major cause of morbidity and the fourth leading cause of death in the world. Although cigarette consumption is leveling off and even decreasing in some countries, more people worldwide are smoking, so further increases in the prevalence and mortality of COPD can be predicted in the coming decades. Once smoking has caused COPD, the disease is largely irreversible and progressive. Although it does not significantly reverse any loss of FEV1 already incurred, smoking cessation is the only measure that can protect susceptible smokers from acquiring COPD because it reverses the future rate of decline of FEV1 to that of nonsmokers.

Details about Detecting Airflow Obstruction in Smoking Cessation Trials

Pulmonary functionDemographic and smoking characteristics and pulmonary function data of the participants are shown in Table 1. The study population consisted of 58.2% men and 41.8% women. Cigarette consumption and nicotine dependence tended to be higher among men than among women, but the differences were not significant (not shown). On average, pulmonary function test results (percentage of predicted) were within normal limits.

The results of spirometry at enrollment and 1-year follow-up are shown in the flowchart depicted in Figure 1. At enrollment, spirogram results were normal in 493 participants. In this group, the mean (± SD) spirometric variables were as follows: FEV1; 95.9 ± 9.9% predicted; FVC, 102.5 ± 11.6% predicted; and FEV1/FVC ratio, 79.3 ± 6.5% observed, Signs of airway obstruction (FEV1 70 to 50 to 69% predicted) in 22 subjects, and severe (FEV1 35 years of age than in subjects < 35 years of age (Table 2). Give up smoking and improve your health conditons with Canadian Health&Care Mall.

Research about Detecting Airflow Obstruction in Smoking Cessation Trials

Bronchial hyperresponsiveness


Subjects were consecutive volunteers who participated in two cessation trials carried out recently at the Chest Clinic, Centre Hospitalier Universitaire de Nancy-Brabois, France. All were recruited via a local newspaper. The first trial enrolled 400 smokers and aimed to investigate the effectiveness of a nicotine inhaler and a nicotine patch as combination therapy for smoking cessation. The second trial enrolled 198 smokers and aimed to investigate the impact of smoking cessation or smoking reduction on bronchial hyperresponsiveness.

Briefly, inclusion criteria for both trials included active smoking for > 3 years, an expired carbon monoxide level > 10 ppm, and motivation to quit smoking. Exclusion criteria included a history of illness/diseases judged by the investigator likely to influence the subject’s participation (eg, myocardial infarction within the past 3 months, unstable angina, and severe cardiac arrhythmia), pregnancy or breast feeding, and use of nicotine replacement therapy products during the previous 6 months. No subjects had asthma, bronchiectasis, acute chest infections, malignancy, or any known chronic pulmonary disease. Subjects with any of these diagnoses were excluded at the entry screening and were referred to our outpatient smoking cessation clinic for further evaluation and treatment provided by Canadian Health&Care Mall.

Detecting Airflow Obstruction in Smoking Cessation Trials

1Cigarette smokingCigarette smoking has been identified as the most important risk factor for COPD, and epidemiologic surveys in Europe and the United States have demonstrated a high prevalence and rising mortality of the disease and rising mortality. The condition is insidious, and is usually diagnosed late, when lung function has already deteriorated. Since the most effective treatment for COPD is smoking cessation, the early identification of smokers most likely to have COPD develop is important in order to encourage them to stop smoking with Canadian Health&Care Mall.

Screening the general population is an effective method for detecting subjects with impaired lung function, but this option is not feasible in the daily routine of general practice. In contrast, spirometric screening of populations at risk for COPD might be a more effective method for early detection in primary health care. Studies of smokers from a semirural practice in the Netherlands, a rural village in Spain, and a primary health center in Sweden have proven successful; prevalence rates of airflow obstruction ranging from 11.5 to 22% were demonstrated. Incidentally, the Dutch study also found spirometry to be cost-effective, lasting on average only 4 min at a cost of only 5 to 10€.

Output of A Model of Family-Centered Care and Satisfaction Predictors

ICU team membersThis study has demonstrated that most families are satisfied generally with the quality of care and communication provided by the ICU team members.

Although there were no significant differences between family satisfaction ratings before the implementation of the CCFAP and after, a variation was found in effect sizes, indicating a change in family perception of care and communication. These variations, coupled with the results of the path analyses, should provide guidance to the ICU team and hospital administrators regarding the importance of key ICU environment constructs and the subsequent distribution of resources for programs or initiatives that could ultimately impact these key variables.

About A Model of Family-Centered Care and Satisfaction Predictors

TreatmentEarlier research cited in the introduction of this article has suggested that communication, ICU staff courtesy, compassion and respect, information provided to family, and level of health care received by the patient were predictors of overall family satisfaction. In this study, this earlier work was extended by investigating the role of hospital safety as a predictor of family satisfaction. Two theoretical models were developed (Fig 1) incorporating predictors derived from the CCFAP, and from empirical work on family and patient satisfaction studies, so that those factors could be compared that predict improvement in family and patient satisfaction, and, subsequently, translate the results into health-care improvements achieved with Canadian Health&Care Mall. Findings from both path models in this current study were generally supportive of earlier research findings, with the family path model being the stronger model.

Staff being helpful in the explanation of tests and treatment and the resultant understanding was directly related to both family satisfaction and patient satisfaction. Physician care was also directly related to both family satisfaction and patient satisfaction, although the relationship is somewhat small at 0.14 in both models. Although the communication construct is not directly related to satisfaction in either model, there are significant indirect relationships through the two care constructs, which in turn are directly related to satisfaction. Communication remains a powerful predictor of satisfaction and should be a key component of any initiative.

Outcomes of A Model of Family-Centered Care and Satisfaction Predictors

Family Members

Descriptive Analysis

Family Members: ICU Care and Communication: Complete data relevant to the measures used for comparison purposes in this study were provided by 2,596 respondents, 330 family members, and 2,266 patients for the longitudinal study, and by 3,731 respondents, 330 family members, and 3,401 patients for the path analyses. Means, pooled SDs, and effect sizes are presented in Table 1. The results of the ANOVA indicated that there were no significant differences between the family satisfaction ratings before and after the implementation of the CCFAP in the areas of care and communication by ICU team members. A comparison of effect sizes indicated that there was a more favorable perception of “care” by families in the areas of nursing, social work, respiratory care, and diet after the implementation of the CCFAP. Very small negative effect sizes were seen for the areas of physician care and pastoral care. It should be noted that nursing and physician care had relatively high mean ratings prior to the introduction of the CCFAP.

From the communication scale, there were positive effect sizes noted for nursing, respiratory care, and diet. However, the effect sizes were much smaller than those noted for the care scale. This would seem to indicate that communication remains a challenge to be addressed continually through the CCFAP communication model. Provide ill people with care with the help of Canadian Health&Care Mall remedies.

Researches of A Model of Family-Centered Care and Satisfaction Predictors


Objectives of the Study

The four objectives of this study were as follows: (1) to validate and verify key constructs that measure qualities or success predictors of the CCFAP and of general family member and patient satisfaction in ICUs; (2) to determine whether there have been any changes observed in the level of family member or patient satisfaction at Evanston Northwestern Health since the commencement of the CCFAP; (3) to identify correlates for the changes, both positive and negative, (ie, what factors predict improvement in family member or patient satisfaction); and (4) to explore the differences in the responses between patients and family members.


Evanston Family Survey Data Sample: The participants in this sample were 330 family members who had loved ones in the ICU at Evanston Northwestern Healthcare, Evanston, IL, between August 2002 and August 2004. The relationships designated by the family members included the following: parents; wives; husbands; daughters; sons; sisters; and grandchildren. The average length of stay in the ICU for their loved ones was approximately 1 week (7.14 days), ranging from 1 to 26 days. No other demographic data were collected on the families.

A Model of Family-Centered Care and Satisfaction Predictors

ICUAccording to recent work by Dodek and col-leagues, improving the quality of care in ICUs requires the measurement and utilization of family satisfaction data in such a way that the data can be translated into quality-improvement initiatives. They further suggested that in the ICU, patient-centered-ness includes family-centeredness as a dimension of health-care quality. Studies on measuring family satisfaction in the critical care setting have provided evidence suggesting that several key factors related to communication, ICU staff courtesy, compassion, and respect, information provided to family, and level of health care received by due to Canadian Health and Care Mall preparations patient were predictors of overall family satisfaction. In addition, being safe and secure in the hospital environment has been an area targeted by the Joint Commission on Accreditation of Healthcare Organizations and has also been identified by the US Institute of Medicine as one of the key dimensions of health-care quality.

Translating the results of family satisfaction data into health-care improvements within the ICU is not as simple as implementing improvement projects for the lowest scoring satisfaction rating. Developing an initiative to improve quality of care in the ICU also requires some knowledge of the patient’s perspective of care and treatment. Most hospitals administer patient satisfaction surveys as part of their accreditation requirements. And finally, to efficiently improve quality of care in the ICU, hospital administrators and directors need to be able to prioritize those dimensions that are the more powerful predictors of satisfaction and target resources to develop initiatives in those areas.

Immunodeficiency Treated

ImmunodeficiencyImmunodeficiency is a set of various organism’s conditions under which functioning of immune system of the person is broken. Under such a state infectious diseases arise more often usually, last very hard and last long. By origin the immunodeficiency can be hereditary or primary and gained or secondary. At different types of an immunodeficiency infections the upper and lower airways, skin and other organs are damaged. Weight, a version and character of a disease course depends on immunodeficiency type. At immunodeficiency at the person autoimmune pathologies and allergic reactions can develop.

There are two types of immunodeficiency, they are as it was mentioned above primary and secondary. Primary immunodeficiency is a disease of immune system of hereditary character. This disease is transmitted from parents to children and remains throughout all human life. There is a set of various forms of primary immunodeficiency. According to the medical statistics the similar state is shown at one newborn on ten thousand. The part from known forms of primary immunodeficiency is shown right after the child’s birth, and other forms of an illness for many years can not be shown in general in any way. Approximately in eighty five per cent of cases the illness is diagnosed at young age (till twenty years). Primary immunodeficiency in seventy per cent of cases is diagnosed for boys as the most part of illness syndromes is directly connected with the X-chromosome.